Factors Influence Adherence Treatment Drugs-Resistant Tuberculosis Client
DOI:
https://doi.org/10.32584/jikj.v3i2.553Keywords:
adherence, drugs-resistan, success-rate, tuberculosisAbstract
The success rate of drug-resistant tuberculosis treatment in the world is still low. Success rates are affected by medication adherence, while loss to follow-up (LTFU) is still found in patients with drug-resistant tuberculosis. It is important to know the factors that influence adherence to make an effort to increase the success rate of drug resistant tuberculosis treatment. The aim is to systematically identify the factors that influence adherence that result in treatment failure in patients with drug-resistant tuberculosis. Systematic reviews are used by searching online database articles (EBSCO Hosts, Clinical Keys, SAGE Publications, and Science Direct). The keywords used are "drug resistant" AND "tuberculosis" AND "adherence" AND "success rate". Analysis by the authors of 355 articles between 2015 and 2020, 10 relevant articles found that the most common factor influences adherence to drug-resistant tuberculosis treatment. It was concluded that the factors that influenced medication adherence were disease severity, comorbidity
References
Ae, Y., Yee, S., Jo, K., & Jin, H. (2013). Impact of Diabetes on Treatment Outcomes and Long-Term Survival in Multidrug-Resistant Tuberculosis, 472–478. https://doi.org/10.1159/000348374
Aibana, O., Bachmaha, M., Krasiuk, V., Rybak, N., Flanigan, T. P., Petrenko, V., & Murray, M. B. (2017). Risk factors for poor multidrug-resistant tuberculosis treatment outcomes in Kyiv, 1–7. https://doi.org/10.1186/s12879-017-2230-2
Aibana, O., Dauria, E., Kiriazova, T., Makarenko, O., Bachmaha, M., Rybak, N., … Murray, M. B. (2020). Patients ’ perspectives of tuberculosis treatment challenges and barriers to treatment adherence in Ukraine : a qualitative study. https://doi.org/10.1136/bmjopen-2019-032027
Atif, M., Bashir, A., Ahmad, N., Fatima, R. K., Saba, S., & Scahill, S. (2017). Predictors of unsuccessful interim treatment outcomes of multidrug resistant tuberculosis patients. BMC Infectious Diseases, 17(1), 1–13. https://doi.org/10.1186/s12879-017-2746-5
Awad, M., El-din, T., Atef, H., & Halim, A. (2015). Adverse reactions among patients being treated for multi-drug resistant tuberculosis in Egypt from July 2006 to January 2009. Egyptian Journal of Chest Diseases and Tuberculosis, 64(3), 657–664. https://doi.org/10.1016/j.ejcdt.2015.05.011
Chem, E. D., Van Hout, M. C., & Hope, V. (2019). Treatment outcomes and antiretroviral uptake in multidrug-resistant tuberculosis and HIV co-infected patients in Sub Saharan Africa: A systematic review and meta-analysis. BMC Infectious Diseases, 19(1), 1–9. https://doi.org/10.1186/s12879-019-4317-4
De Schacht, C., Mutaquiha, C., Faria, F., Castro, G., Manaca, N., Manhiça, I., & Cowan, J. (2019). Barriers to access and adherence to tuberculosis services, as perceived by patients: A qualitative study in Mozambique. PLoS ONE, 14(7), 1–12. https://doi.org/10.1371/journal.pone.0219470
El Hamdouni, M., Bourkadi, J. E., Benamor, J., Hassar, M., Cherrah, Y., & Ahid, S. (2019). Treatment outcomes of drug resistant tuberculosis patients in Morocco: Multi-centric prospective study. BMC Infectious Diseases, 19(1), 1–8. https://doi.org/10.1186/s12879-019-3931-5
Gadallah, M. A., Mokhtar, A., Rady, M., El-moghazy, E., Fawzy, M., & Khalil, S. (2016). ScienceDirect Prognostic factors of treatment among patients with multidrug-resistant tuberculosis in Egypt. Journal of the Formosan Medical Association, 115(11), 997–1003. https://doi.org/10.1016/j.jfma.2015.10.002
Gebreweld, F. H., Kifle, M. M., Gebremicheal, F. E., Simel, L. L., Gezae, M. M., Ghebreyesus, S. S., … Wahd, N. G. (2018). Factors influencing adherence to tuberculosis treatment in Asmara, Eritrea: a qualitative study. Journal of Health, Population, and Nutrition, 37(1), 1. https://doi.org/10.1186/s41043-017-0132-y
Heyckendorf, J., Olaru, I. D., Ruhwald, M., & Lange, C. (2014). Getting Personal Perspectives on Individualized Treatment Duration in Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis, 190(4), 374–383. https://doi.org/10.1164/rccm.201402-0363PP
Hirasen, K., Berhanu, R., Evans, D., Rosen, S., Sanne, I., & Long, L. (2018). High rates of death and loss to follow-up by 12 months of rifampicin resistant TB treatment in South Africa. PLoS ONE, 13(10), 1–14. https://doi.org/10.1371/journal.pone.0205463
Hutchison, C., Khan, M. S., Yoong, J., Lin, X., & Coker, R. J. (2017). Financial barriers and coping strategies: a qualitative study of accessing multidrug-resistant tuberculosis and tuberculosis care in Yunnan, China. BMC Public Health, 17(1), 1–11. https://doi.org/10.1186/s12889-017-4089-y
Jaber, A. A. S., & Ibrahim, B. (2019). Evaluation of risk factors associated with drug-resistant tuberculosis in Yemen: Data from centres with high drug resistance. BMC Infectious Diseases, 19(1), 1–9. https://doi.org/10.1186/s12879-019-4069-1
Javaid, A., Ullah, I., Masud, H., Basit, A., Ahmad, W., Butt, Z. A., & Qasim, M. (2018). Predictors of poor treatment outcomes in multidrug-resistant tuberculosis patients: a retrospective cohort study. Clinical Microbiology and Infection, 24(6), 612–617. https://doi.org/10.1016/j.cmi.2017.09.012
Kassa, G. M., Teferra, A. S., Wolde, H. F., Muluneh, A. G., & Merid, M. W. (2019). Incidence and predictors of lost to follow-up among drug-resistant tuberculosis patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A retrospective follow-up study. BMC Infectious Diseases, 19(1), 1–11. https://doi.org/10.1186/s12879-019-4447-8
Ketema, D. B., Muchie, K. F., & Andargie, A. A. (2019). Time to poor treatment outcome and its predictors among drug-resistant tuberculosis patients on second-line anti-Tuberculosis treatment in Amhara region, Ethiopia: Retrospective cohort study. BMC Public Health, 19(1), 1–11. https://doi.org/10.1186/s12889-019-7838-2
Khan, I., Ahmad, N., Khan, S., Muhammad, S., Ahmad Khan, S., Ahmad, I., … Atif, M. (2019). Evaluation of treatment outcomes and factors associated with unsuccessful outcomes in multidrug resistant tuberculosis patients in Baluchistan province of Pakistan. Journal of Infection and Public Health, 12(6), 809–815. https://doi.org/10.1016/j.jiph.2019.04.009
Kiplangat, R., Sang, A., Obwoge, R. O., Kangethe, S., & Ayiro, L. P. (2017). Patient Factors Which Contribute to Non-adherence to TB Treatment in Kericho and Nakuru Counties of Kenya, 5(4), 329–334. https://doi.org/10.11648/j.sjph.20170504.18
Krasniqi, S., Jakupi, A., Daci, A., Tigani, B., Jupolli-krasniqi, N., Pira, M., … Neziri, B. (2017). Tuberculosis Treatment Adherence of Patients in Kosovo, 2017.
Li, D., Ge, E., Shen, X., & Wei, X. (2016). Risk Factors of Treatment Outcomes for Multi-drug Resistant Tuberculosis in Shanghai, 2009-2012. Procedia Environmental Sciences, 36, 12–19. https://doi.org/10.1016/j.proenv.2016.09.003
McNally, T. W., De Wildt, G., Meza, G., & Wiskin, C. M. D. (2019). Improving outcomes for multi-drug-resistant tuberculosis in the Peruvian Amazon - A qualitative study exploring the experiences and perceptions of patients and healthcare professionals. BMC Health Services Research, 19(1), 1–18. https://doi.org/10.1186/s12913-019-4429-y
Mesfin, E. A., Beyene, D., Tesfaye, A., Admasu, A., Addise, D., Amare, M., … Tessema, B. (2018). Drug-resistance patterns of Mycobacterium tuberculosis strains and associated risk factors among multi drug-resistant tuberculosis suspected patients from Ethiopia. PLOS ONE, 13(6), e0197737. https://doi.org/10.1371/journal.pone.0197737
Patel, S. V., Nimavat, K. B., Alpesh, P. B., Shukla, L. K., Shringarpure, K. S., Mehta, K. G., & Joshi, C. C. (2016). Treatment outcome among cases of multidrug-resistant tuberculosis (MDR TB) in Western India: A prospective study. Journal of Infection and Public Health, 9(4), 478–484. https://doi.org/10.1016/j.jiph.2015.11.011
Tola, H. H., Tol, A., Shojaeizadeh, D., & Garmaroudi, G. (2015). Tuberculosis treatment non-adherence and lost to follow up among TB patients with or without HIV in developing countries: A systematic review. Iranian Journal of Public Health, 44(1), 1–11.
Torres, N. M. C., RodrÃguez, J. J. Q., Andrade, P. S. P., Arriaga, M. B., & Netto, E. M. (2019). Factors predictive of the success of tuberculosis treatment: A systematic review with meta-analysis. PLoS ONE, 14(12), 1–25. https://doi.org/10.1371/journal.pone.0226507
Van, L. H., Phu, P. T., Vinh, D. N., Son, V. T., Hanh, N. T., Thanh, L., & Nhat, H. (2020). Risk factors for poor treatment outcomes of 2266 multidrug-resistant tuberculosis cases in Ho Chi Minh City : a retrospective study, 1–10.
Waithaka, S., Kei, R., & Mbugua, G. (2019). Factors that Influence the Interruption of Tuberculosis Treatment in Imenti, 7(2).
WHO. (2019). Global tuberculosis report 2019. Geneva: World Health Organization.
Workneh, M. H., Bjune, G. A., & Yimer, S. A. (2016). Diabetes mellitus is associated with increased mortality during tuberculosis treatment : a prospective cohort study among tuberculosis patients in South- Eastern Amahra Region , Ethiopia. Infectious Diseases of Poverty, 1–10. https://doi.org/10.1186/s40249-016-0115-z
Zhang, L., Meng, Q., Chen, S., Zhang, M., Chen, B., Wu, B., … Jia, Z. (2018). Treatment outcomes of multidrug-resistant tuberculosis patients in Zhejiang, China, 2009–2013. Clinical Microbiology and Infection, 24(4), 381–388. https://doi.org/10.1016/j.cmi.2017.07.008
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