• Arslan Kamil Aries Poltekkes Kemenkes Semarang
  • Budi Widyanto Prodi Magister Terapan Keperawatan, Poltekkes Kemenkes Semarang
  • Sudirman Sudirman Prodi Magister Terapan Keperawatan, Poltekkes Kemenkes Semarang



factors, quality of life, leukemia


Leukemia is a malignant disease that attacks the hematopoiesis system, causing uncontrolled blood cell proliferation. Quality of life is one indicator that can be used to see the welfare conditions of patients suffering from chronic diseases such as leukemia. This review literature aims to find out the factors that influence the quality of life of leukemia patients. Literature search through Google Scholar, EBSCO, Springer Link, Elsevier, Sage databases using keywords: factors, quality of life, leukemia. The journals taken have a range from 2018 to 2020, which are then filtered according to the inclusion criteria set by the author. The results of the review indicate that there are several factors that affect the quality of life in leukemia patients, namely the therapeutic treatment undertaken, the patient's environment, and the role of care giver. Proper management of leukemia patients will improve the quality of life of these patients, and vice versa.


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Antioxidant and Selective Anticancer Activities of Two Euphorbia Species in Human

Acute Myeloid Leukemia. Biomedicine and Pharmacotherapy, 90, 375–385.

Bult, M. K., Van Bindsbergen, K. L. A., Schepers, S. A., De Ridder-Sluiter, H. G., Verhaak, C. M.,

Van Litsenburg, R. R. L., … Grootenhuis, M. A. (2019). Health-Related Quality of Life of

Adolescents With Cancer During The First Year of Treatment. Journal of Adolescent and

Young Adult Oncology, 8(5), 616–622.

Choo, C. C., Chew, P. K. H., Tan, P., Choo, J. Q., Choo, A. M. H., Ho, R. C., & Quah, T. C. (2019).

Health-Related Quality of Life in Pediatric Patients with Leukemia in Singapore: A

Cross-Sectional Pilot Study. International Journal of Environmental Research and Public

Health, 16(12), 1–10.

Corella Aznar, E. G., Ayerza Casas, A., Carboné Bañeres, A., Calvo Escribano, M. Á. C., Labarta

Aizpún, J. I., & Samper Villagrasa, P. (2019). Quality of Life and Chronic Health

Conditions in Childhood Acute Leukaemia Survivors. Medicina Clínica (English Edition),

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Efficace, F., Stagno, F., Iurlo, A., Breccia, M., Cottone, F., Bonifacio, M., … Rosti, G. (2020).

Health-Related Quality of Life of Newly Diagnosed Chronic Myeloid Leukemia Patients

Treated with First-Line Dasatinib Versus Imatinib Therapy. Leukemia, 34(2), 488–498.

El-Jawahri, A., Abel, G. A., Traeger, L., Waldman, L., Markovitz, N., VanDusen, H., … Greer, J. A.

(2019). Quality of Life and Mood of Older Patients with Acute Myeloid Leukemia (AML)

Receiving Intensive and Non-Intensive Chemotherapy. Leukemia, 33(10), 2393–2402.

Horvath Walsh, L. E., Rider, A., Piercy, J., Pike, J., Wilson, S., Pandya, B. J., & Medeiros, B. C.

(2019). Real-World Impact of Physician and Patient Discordance on Health-Related

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(2019). A Real-World, Cross-Sectional, Community Survey of Symptoms and HealthRelated Quality of Life of Adults with Acute Myeloid Leukemia. Future Oncology, 15(16),


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Trask, P. C., Cella, D., Powell, C., Reisman, A., Whiteley, J., & Kelly, V. (2013). Health-related

quality of life in chronic myeloid leukemia. Leukemia Research, 37(1), 9–13.

Wang, C., Yan, J., Chen, J., Wang, Y., Lin, Y. C., Hu, R., & Wu, Y. (2020). Factors Associated with

Quality of Life of Adult Patients with Acute Leukemia and Their Family Caregivers in

China: A Cross-Sectional Study. Health and Quality of Life Outcomes, 18(1), 1–9.